WELCOME TO THE MAHMOUDI LAB
“My lab investigates the molecular mechanisms in disease. We use insights from our fundamental research to address clinical challenges in human diseases, including HIV infection, liver and bladder cancer. Specifically, the research aims of my group are to decipher the precise molecular and functional consequence of chromatin mediated gene regulation in pathogenesis resulting from viral infection and/or tumorigenesis and to develop pharmacological approaches to modulate this process.”
Tokameh Mahmoudi
LATEST NEWS
JUST PUBLISHED
Catchet-MS identifies IKZF1-targeting thalidomide analogues as novel HIV-1 latency reversal agents
JUST PUBLISHED
DEAD-ly Affairs: The Roles of DEAD-Box Proteins on HIV-1 Viral RNA Metabolism
JUST PUBLISHED
A Two-Color Haploid Genetic Screen Identifies Novel Host Factors Involved in HIV-1 Latency
JUST PUBLISHED
Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma. ELife 2021
JUST PUBLISHED
Selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir. Nat Comm 2021
IN THE MEDIA
Researchers from the Netherlands find a way to incite HIV cells to self-destruct. First step to cure?
AMAZING ERASMUS
All cells in our body have the same genetic material. Why then does one cell become a liver cell and the other skin cell or brain cell?